3-Fluoro-4-methylbenzonitrile (CAS: 170572-49-3) – Fluorinated Aromatic Building Block

3-Fluoro-4-methylbenzonitrile

**Product Name:** 3-Fluoro-4-methylbenzonitrile
**CAS Number:** 170572-49-3
**Molecular Formula:** C₈H₆FN
**Molecular Weight:** 135.14 g/mol
**Purity (GC):** ≥ 98.0% [*Placeholder – Certificate of Analysis available upon request*]

## Product Overview

3-Fluoro-4-methylbenzonitrile is a fluorinated aromatic nitrile that serves as an important intermediate in the synthesis of pharmaceuticals and agrochemicals. The fluorine atom at the 3-position imparts enhanced metabolic stability and membrane permeability to drug candidates.

## Applications in Research

– **Pharmaceutical Intermediate:** Key starting material for the synthesis of angiotensin receptor blockers (ARBs) and other cardiovascular agents.
– **Fluorine Incorporation:** The strategic fluorine atom improves pharmacokinetic properties (ADME) in lead optimization.
– **Nitrile Transformations:** The nitrile group can be hydrolyzed to carboxylic acids, reduced to amines, or converted to tetrazoles.

## Analytical Data

| Parameter | Specification |
|———–|—————|
| Appearance | White to off-white crystalline solid |
| Purity (GC) | ≥ 98.0% (COA available) |
| Melting Point | 52–55 °C |
| Storage | Store at room temperature, protected from moisture |
| Shipping | FOB Shanghai |

## Pricing

| Package Size | Price (USD) |
|————-|————-|
| 5 g | Please inquire |
| 25 g | Please inquire |
| 100 g | Please inquire |

All prices are quoted FOB Shanghai. Please contact us for current pricing and volume discounts.

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