L-tert-Leucine Amide Hydrochloride (CAS 75158-12-2) — Chiral Building Block

L-tert-Leucine Amide Hydrochloride

CAS: 75158-12-2 | MW: 182.65 g/mol | Purity: ≥97%

L-tert-Leucine amide hydrochloride

Product Specifications

PropertyValue
CAS Number75158-12-2
Molecular FormulaC6H15ClN2O
Molecular Weight182.65 g/mol
Purity≥97%
Chemical Name(2S)-2-Amino-3,3-dimethylbutanamide hydrochloride
CategoryChiral Building Block / Pharmaceutical Intermediate

Description

L-tert-Leucine amide hydrochloride (CAS 75158-12-2) is a chiral amino acid amide derivative featuring a sterically hindered tert-butyl side chain. The compound serves as a valuable building block in peptide synthesis and medicinal chemistry, particularly in the preparation of protease inhibitors and other enzyme-targeting pharmaceuticals. The bulky tert-leucine moiety imparts significant conformational constraint and metabolic stability to drug molecules.

Applications

  • Peptide synthesis and modification
  • Protease inhibitor development
  • Chiral building block for medicinal chemistry
  • Pharmaceutical intermediate synthesis

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