7-Bromo-1H-indazole (CAS: 53857-57-1) – Key Heterocyclic Scaffold for Drug Discovery

7-Bromo-1H-indazole

**Product Name:** 7-Bromo-1H-indazole
**CAS Number:** 53857-57-1
**Molecular Formula:** C₇H₅BrN₂
**Molecular Weight:** 197.03 g/mol
**Purity (HPLC):** ≥ 97.0% [*Placeholder – Certificate of Analysis available upon request*]

## Product Overview

7-Bromo-1H-indazole is a valuable halogenated indazole derivative used extensively in medicinal chemistry programs targeting oncology, neurology, and inflammatory disease pathways. The 7-bromo substituent provides a versatile handle for late-stage functionalization.

## Applications in Research

– **Kinase Inhibitor Discovery:** Used as a core scaffold for the synthesis of selective kinase inhibitors, particularly targeting the indazole-binding hinge region of protein kinases.
– **Suzuki Coupling:** The C7 bromide facilitates palladium-catalyzed cross-coupling for rapid SAR exploration.
– **C-H Activation Studies:** Serves as a model substrate for C-H functionalization methodology development.

## Analytical Data

| Parameter | Specification |
|———–|—————|
| Appearance | White to off-white crystalline solid |
| Purity (HPLC) | ≥ 97.0% (COA available) |
| Melting Point | 148–152 °C |
| Solubility | Soluble in DMSO, DCM, EtOAc |
| Storage | Store at 2–8 °C, protected from light |
| Shipping | FOB Shanghai |

## Pricing

| Package Size | Price (USD) |
|————-|————-|
| 1 g | Please inquire |
| 5 g | Please inquire |
| 25 g | Please inquire |

All prices are quoted FOB Shanghai. Contact us for current pricing and lead times.

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